JIVA-25™ is the world's first dedicated preclinical oxygen imager.  JIVA-25™ delivers 3D partial oxygen pressure maps in vitro and in vivo in small animals based on pulse electron paramagnetic resonance oxygen imaging principle invented by O2M's co-founders.

JIVA-25™ is a 25 mT instrument and provides pO2 maps in live tissues in vitro and in vivo with high spatial, temporal, and pO2 resolution. 

 Oxygen   Measurement Core 

O2M’s "Oxygen Measurement Core" is a contract research facility. It provides full cycle in vitro and small animal in vivo oxygen measurement services. All experiments are performed using O2M’s preclinical oxygen imager, JIVA-25™ that can accommodate sample size up to 40 mm. O2M can carry research projects to its full  experiment cycle, from sample preparation and cell seeding to in vitro and small animal in vivo oxygen imaging along with biologic assays and histology assessments, and provide publication quality data/images, and support your submission to peer reviewed journals leading up to publication of the work. 

Example projects:

  1. In vitro longitudinal (hours/days) oxygen assessment of acellular and cell loaded biomaterials, tissue grafts, and cell encapsulation devices

  2. In vivo small animal  longitudinal (days/weeks/months) assessment of biomaterials, tissue grafts, and cell encapsulation devices

  3. In vivo oxygen assessment of tumor growth and response to treatments

Example samples: 

  1. Biomaterials: Gelatin, Alginate, Agarose, Collagen, Chitosan, PLGA, and other combination experimental biomaterials

  2. Cell encapsulation devices: flat sheet, oxygen generating,3D printed vascular devices

  3. Small animal tumor models


O2M’s clients are academic institutions, research foundations, and industry partners. Reach out to us to discuss your research project!

See our recent publication from Oxygen Measurement Core as an example